SeMPI 2.0

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Record: NZ_CP048641.1

Comment: NZ_CP048641.1 Streptomyces aureoverticillatus strain HN6 chromosome, complete genome

Change record: 0 1


Cluster Block Type DB screening Cluster browser Domains Modify scaffold Specificity Smiles Postsynthetic modifications Figure
8 1 pks-nrps Show Open Show Scaffold Input methylmalonyl * malonyl * malonyl * malonyl * malonyl * methylmalonyl * methylmalonyl * malonyl * malonyl * methylmalonyl * malonyl * methylmalonyl * methylmalonyl * malonyl * methylmalonyl * malonyl * malonyl * methylmalonyl * methylmalonyl * malonyl * methylmalonyl * F N[C@H](Cc1ccccc1)C(O)C(C)C(O)CC=CC(O)CC(O)CC=C(C)C(O)C(C)C(O)CC(O)CC(O)C(C)C(O)CC=C(C)C(O)C(C)C=CC(O)C(C)C=CCCC(O)C(C)C(O)C(C)CCC=C(C)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:1 * Sphingo:0 * 5-Ring:1 NH2 OH OH OH OH OH OH OH OH OH OH OH OH OH O OH
5 1 pks-nrps Show Open Show Scaffold Input methylmalonyl * methylmalonyl * malonyl * methylmalonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * methylmalonyl * malonyl * methylmalonyl * malonyl * methylmalonyl * malonyl * malonyl * malonyl * F CCC(=O)N[C@H](Cc1ccccc1)C=C(C)C(O)C(C)C=CC=C(C)C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(=O)CC(O)C(C)CCC(O)C(C)C(O)CC(O)C(C)C=CC=CC(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:1 * Sphingo:0 * 5-Ring:0 O NH OH OH OH OH OH OH OH O OH OH OH OH O OH
37 1 nrps Show Open Show Scaffold Input L * A * V * L * L * orn * T * orn * V * L N[C@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCCN)C(=O)N[C@H](C(O)C)C(=O)N[C@@H](CCCN)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](CC(C)C) None NH2 O NH O NH O NH O NH O NH NH2 O NH OH O NH H2N O NH O NH
4 1 nrps Show Open Show Scaffold Input D * T * S * dhb * T * T * S * F * G * F N[C@H](Cc1ccccc1)C(=O)N[C@H](CC(=O)O)C(=O)N[C@H](C(O)C)C(=O)N[C@H](CO)C(=O)Oc1c(O)c(ccc1)C(=O)N[C@H](C(O)C)C(=O)N[C@H](C(O)C)C(=O)N[C@H](CO)C(=O)N[C@H](Cc1ccccc1)C(=O)N(C)CC(=O)O None H2N O NH O OH O NH HO O NH OH O O OH O NH HO O NH OH O NH OH O NH O N O HO
36 1 nrps-pks Show Open Show Scaffold Input F * F * A * T * F * F * unknown * W * dhb Oc1c(O)c(ccc1)N[C@H](Cc1ccccc1)C(=O)C(*)C(=O)N[C@H](CC1=CNC(=C12)C=CC=C2)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C)C(=O)N[C@H](C(O)C)C(=O)N[C@H](Cc1ccccc1)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 OH OH NH O * O NH NH O NH O NH O NH O NH OH O NH O OH
8 2 nrps-pks Show Open Show Scaffold Input F * methylmalonyl * methylmalonyl * methylmalonyl * malonyl * methylmalonyl * malonyl N[C@H](Cc1ccccc1)C=C(C)C=C(C)C=C(C)CCC(=O)C(C)C(=O)CC(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:1 * Sphingo:0 * 5-Ring:1 NH2 O O O OH
16 3 nrps Show Open Show Scaffold Input W * A * A * A * A * A N[C@@H](CC1=CNC(=C12)C=CC=C2)C(=O)N[C@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 NH O NH O NH O NH O NH O NH O OH
13 1 nrps Show Open Show Scaffold Input F * A * F * L * F * L N[C@@H](Cc1ccccc1)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)O None H2N O NH O NH O NH O N O NH O HO
2 1 nrps Show Open Show Scaffold Input V * A * A * V * A * V N[C@@H](C(C)C)C(=O)N[C@H](C)C(=O)N[C@@H](C)C(=O)N(C)[C@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O NH O NH O N O NH O NH O OH
7 1 nrps Show Open Show Scaffold Input P * P * L * P * P N[C@H](C1CCCN1)C(=O)N[C@H](C1CCCN1)C(=O)N[C@H](C1CCCN1)C(=O)N[C@H](C1CCCN1)C(=O)N[C@H](CC(C)C)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 NH O NH NH O NH NH O NH NH O NH O OH
3 1 nrps Show Open Show Scaffold Input F * T * A * F C(=O)N[C@H](Cc1ccccc1)C(=O)N(C)[C@H](C(O)C)C(=O)N[C@H](C)N[C@H](Cc1ccccc1) Glyco:1 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH O N HO O NH NH
17 1 nrps Show Open Show Scaffold Input dhb * F * W Oc1c(O)c(ccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=CNC(=C12)C=CC=C2) None OH OH O NH O NH NH
25 1 nrps Show Open Show Scaffold Input F * F * D N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CC(=O)O)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O NH O NH O OH O OH
2 2 pks Show Open Show Scaffold Input methylmalonyl * malonyl * malonyl C(C)C=CC=C Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0
16 2 pks Show Open Show Scaffold Input methylmalonyl * malonyl * methylmalonyl C(C)C=CC=C(C) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0
35 4 nrps Show Open Show Scaffold Input S * T * horn N[C@@H](CO)C(=O)N[C@@H](C(O)C)C(=O)N[C@H](CCCNO) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N OH O NH OH O NH NH OH
14 1 nrps Show Open Show Scaffold Input F * F N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1) None NH2 O NH
12 1 nrps Show Open Show Scaffold Input F * E N[C@H](Cc1ccccc1)C(=O)N[C@H](CCC(=O)O) None NH2 O NH O OH
27 1 nrps Show Open Show Scaffold Input A * E N[C@H](C)C(=O)N[C@H](CCC(=O)O) None NH2 O NH O OH
1 1 pks-nrps Show Open Show Scaffold Input malonyl * F C(O)CC(=O)N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO O NH
38 1 nrps Show Open Show Scaffold Input S * P C(=O)N[C@H](CO)C(=O)N[C@H](C1CCCN1)C(=O)O None O NH OH O NH NH O HO
9 1 nrps-pks Show Open Show Scaffold Input P * malonyl N[C@H](C1CCCN1)C(=O)C Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 NH O
40 1 pks-nrps Show Open Show Scaffold Input malonyl * F C(O)CC(=O)N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO O NH
35 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
35 3 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
39 1 nrps Show Open Show Scaffold Input D C(=O)N[C@H](CC(=O)O) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH O OH
35 2 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
15 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) None HO HO
6 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
10 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
11 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
16 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
18 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
19 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
20 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
21 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
22 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
23 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
24 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
25 2 nrps Show Open Show Scaffold Input N N[C@H](CC(=O)N) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O H2N
26 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
28 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
28 2 pks Show Open Show Scaffold Input malonyl C Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 CH4
29 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
30 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
31 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
32 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
33 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
34 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N

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