SeMPI 2.0

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Record: NZ_CP023699.1

Comment: NZ_CP023699.1 Streptomyces kanamyceticus strain ATCC 12853 chromosome, complete genome

Change record: 0


Cluster Block Type DB screening Cluster browser Domains Modify scaffold Specificity Smiles Postsynthetic modifications Figure
8 1 pks Show Open Show Scaffold Input methylmalonyl * methylmalonyl * malonyl * malonyl * malonyl * malonyl * methylmalonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * malonyl * methylmalonyl C(C)C(O)C(C)C=CC(O)CC(O)CC(O)CC=C(C)C(O)CC=CC=CC=CC(O)CC(O)CC=CC=CC=CC=CC=C(C)C(=O)O Glyco:3 * NO2:0 * Cl:0 * SS:0 * 6-Ring:1 * Sphingo:0 * 5-Ring:0 OH HO HO HO OH OH OH O HO
7 1 nrps Show Open Show Scaffold Input L * aad * F * W * L * hpg * hpg * Y * L * F * F N[C@H](Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCC(=O)O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC1=CNC(=C12)C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CNc1ccc(O)cc1)C(=O)N[C@@H](CNc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](Cc1ccccc1)C(=O)O Glyco:0 * NO2:0 * Cl:1 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O NH O NH O OH O NH O NH NH O NH O NH NH OH O NH NH HO O NH OH O NH O NH O HO
19 2 nrps Show Open Show Scaffold Input S * T * F * D * D * hpg * D * G * N * D * V C(=O)N[C@H](CO)C(=O)N[C@H](C(O)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CC(=O)O)C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](CNc1ccc(O)cc1)C(=O)N[C@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@H](CC(=O)O)C(=O)N[C@H](C(C)C)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH OH O NH HO O NH O NH O OH O NH O OH O NH NH OH O NH O OH O NH O NH O NH2 O NH O OH O NH O OH
5 1 pks-nrps Show Open Show Scaffold Input malonyl * methylmalonyl * malonyl * ethylmalonyl * methylmalonyl * pip * malonyl * malonyl * methylmalonyl * malonyl CC(=O)N1[C@H](CCC1)CCC=CCC(C)C(=O)CC=C(C)C=CC(=O)C(CC)C=C(C) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O N O O
1 1 pks Show Open Show Scaffold Input methylmalonyl * ethylmalonyl * methylmalonyl * methylmalonyl * methylmalonyl * methylmalonyl * methylmalonyl * ethylmalonyl * malonyl C(C)C=C(CC)C=C(C)CC(C)C=C(C)C(O)C(C)C=C(C)CC(CC)C(=O)CC(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 OH O O OH
36 1 pks Show Open Show Scaffold Input malonyl * malonyl * methylmalonyl * malonyl * malonyl * malonyl * malonyl * methylmalonyl * malonyl CC=CC(=O)C(C)C=CC=CCCCCC=C(C)C(O)C Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O OH
39 1 nrps Show Open Show Scaffold Input T * A * W * A * V * F * G * W * P N(C)[C@H](C(O)C)C(=O)N[C@H](C)C(=O)N[C@H](CC1=CNC(=C12)C=CC=C2)C(=O)N[C@H](C)C(=O)N(C)[C@H](C(C)C)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](CC1=CNC(=C12)C=CC=C2)C(=O)N[C@H](C1CCCN1)C(=O)O None NH OH O NH O NH NH O NH O N O NH O NH O NH NH O NH NH O OH
19 1 nrps Show Open Show Scaffold Input hpg * S * V * V * V * S C(=O)N[C@H](CNc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH NH OH O NH HO O NH O NH O NH O NH OH O OH
38 1 nrps Show Open Show Scaffold Input F * F * V * G * A N[C@H](Cc1ccccc1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N[C@H](C(C)C)C(=O)NCC(=O)N[C@H](C)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O N O NH O NH O NH O HO
41 1 nrps Show Open Show Scaffold Input V * V * dhb * F C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)Oc1c(O)c(ccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH O NH O O OH O NH O OH
13 1 nrps Show Open Show Scaffold Input S * P * F * F N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CO)C(=O)N[C@H](C1CCCN1)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O NH O NH HO O NH NH O OH
43 2 nrps-pks Show Open Show Scaffold Input V * P * unknown N[C@H](C(C)C)C(=O)N[C@H](C1CCCN1)C(O)C(*)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O NH NH OH * O OH
26 1 nrps Show Open Show Scaffold Input dhb * T Oc1c(O)c(ccc1)C(=O)N[C@H](C(O)C)C(=O)O None OH OH O NH OH O OH
10 1 pks Show Open Show Scaffold Input malonyl * malonyl CC(=O)C Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O
29 1 nrps Show Open Show Scaffold Input F * E N[C@H](Cc1ccccc1)C(=O)N[C@H](CCC(=O)O) Glyco:2 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O NH O OH
33 1 pks-nrps Show Open Show Scaffold Input malonyl * L CC(=O)N[C@H](CC(C)C) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH
3 1 nrps Show Open Show Scaffold Input dhb * F Oc1c(O)c(ccc1)C(=O)N[C@H](Cc1ccccc1) None OH OH O NH
3 2 nrps Show Open Show Scaffold Input F * F N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1) None NH2 O NH
30 1 nrps Show Open Show Scaffold Input A * E N[C@H](C)C(=O)N[C@H](CCC(=O)O) None NH2 O NH O OH
24 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
25 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
27 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
28 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
31 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
32 1 pks Show Open Show Scaffold Input malonyl C Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 CH4
34 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
35 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
37 1 nrps Show Open Show Scaffold Input A N[C@H](C) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2
39 2 nrps Show Open Show Scaffold Input F C(=O)N[C@H](Cc1ccccc1) None O NH
40 1 pks Show Open Show Scaffold Input unknown C(=O)C(*) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O *
42 1 nrps Show Open Show Scaffold Input F C(=O)N[C@H](Cc1ccccc1)C(=O)O None O NH O OH
42 2 nrps Show Open Show Scaffold Input D C(=O)N[C@H](CC(=O)O)C(=O)O None O NH O OH O OH
43 1 nrps Show Open Show Scaffold Input F C(=O)N[C@H](Cc1ccccc1)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH O OH
44 1 pks Show Open Show Scaffold Input malonyl C=CC(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O OH
45 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
46 1 nrps Show Open Show Scaffold Input aad N[C@H](CCCC(=O)O) None NH2 O OH
2 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
4 1 nrps Show Open Show Scaffold Input C C(=O)N[C@H](CS)C(=O)O Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O NH HS O OH
6 1 pks Show Open Show Scaffold Input unknown C(=O)C(*) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O *
17 2 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
9 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
11 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
12 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
13 2 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
14 1 pks Show Open Show Scaffold Input unknown C(=O)C(*) Glyco:0 * NO2:0 * Cl:1 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 O *
15 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
16 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
16 2 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
17 1 nrps Show Open Show Scaffold Input aad N[C@H](CCCC(=O)O) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 NH2 O OH
18 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
20 1 nrps Show Open Show Scaffold Input dhb Oc1c(O)c(ccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 HO HO
21 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) Glyco:0 * NO2:0 * Cl:0 * SS:0 * 6-Ring:0 * Sphingo:0 * 5-Ring:0 H2N
22 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N
23 1 nrps Show Open Show Scaffold Input F N[C@H](Cc1ccccc1) None H2N

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